German Center for Neurodegenerative Diseases (DZNE) Bonn, Germany
Dr Bano received his PhD in Biochemistry and Biophysics from the University of Padova, Italy in 2002. In 2001, he moved to the laboratory of Prof Pierluigi Nicotera at the MRC Toxicology Unit, University of Leicester, UK. In 2007, he joined the laboratory of Prof Michael O. Hengartner as a postdoc at the Institute of Molecular Biology, University of Zurich, Switzerland. From 2008 until 2009 he was working as a Principal Investigator at the MRC Toxicology Unit, University of Leicester, UK. Since 2009, Daniele Bano is a research group leader at the German Center for Neurodegenerative Diseases (DZNE), Bonn.
Dr Bano focuses on two important topics: 1) Crosstalk between pro-survival signaling pathways and mitochondrial deficiency; 2) Age-dependent chromatin remodelling and neurodegeneration. He is interested in those signaling processes that can affect longevity and may be relevant in the onset of neurodegenerative disorders, including human pathologies causally linked to altered mitochondrial function. As a part of our ongoing projects, he wishes to identify molecular pathways and biologically active molecules capable of ameliorating conditions associated with mitochondrial impairment. The research programme combines the extensive use of genetic approaches in model organisms, including the nematode Caenorhabditis elegans and a range of newly developed transgenic mice. Genetic approaches as well as a number of novel cutting-edge-technologies are routinely used in his laboratory.