Department of Neurobiology, Care Sciences and Society (NVS), Karolinska Institutet, Sweden
Dr Ankarcrona received her PhD in Toxicology from Karolinska Institutet, Sweden in 1996. Then she joined the Greengard lab, Rockefeller University, New York as a post-doctoral fellow. 1998- 2004 she worked as postdoc and research associate at Neurotec, Karolinska Institutet. Since 2005 Dr Ankarcrona is associated professor at NVS (former Neurotec), Karolinska Institutet.
Dr Ankarcrona is specialized in cell death mechanisms and in the role of mitochondria in neurodegeneration. The main focus of Dr Ankarcrona’s research is the mechanisms of functional and structural impairments in mitochondria and mitochondria associated-ER membranes (MAM) in Alzheimer’s disease (AD). Her laboratory uses primary neuronal cultures, cell lines and mouse brain tissue to study AD pathogenic mechanisms. Two recent studies from her group have investigated the modulation of the MAM region in AD brain, AD mouse models and primary hippocampal neurons exposed to oligomeric Aβ (Hedskog et al PNAS 2013) and the generation of Aβ at MAM (Schreiner et al JAD 2015).